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Bulk Sorbents (MN)

Irregular silica phases for HPLC

Irregular silica for analytical applications

  • pH stability 2 – 8
  • Particle sizes 5 µm, 7 µm and 10 µm
Bulk Sorbents

Bulk Sorbents

Available Pack Size: 10gm, 100gm

Modifications POLYGOSIL C18, C8, C4, CN, NO2, NH2, dimethylaminopropyl, Unmodified

Phase Pore size Pore volume Surface (BET) Density Pressure stability
POLYGOSIL 60 60 Å 0.75 ml/g 350 m2/g 0.45 g/ml 600 bar
POLYGOSIL 100 100 Å 1 ml/g 280 m2/g 0.35 g/ml 400 bar
POLYGOSIL 300 300 Å 0.8 ml/g 100 m2/g 0.45 g/ml 400 bar
POLYGOSIL 1000 1000 Å 0.8 ml/g 25 m2/g 0.45 g/ml 300 bar

Irregular silica for preparative applications

  • pH stability 2 – 8
  • Available particle sizes 12 µm, 20 µm, 30 µm, 50 µm, 80 µm and 130 µm
Available Pack Size: 100gm, 1Kg, 5Kg

Modifications POLYGOPREP C18, C8, C4, CN, NH2, Unmodified

Phase Pore size Pore volume Surface (BET) Density Pressure stability
POLYGOPREP 60 60 Å 0.75 ml/g 350 m2/g 0.45 g/ml 600 bar
POLYGOPREP 100 100 Å 1 ml/g 280 m2/g 0.35 g/ml 400 bar
POLYGOPREP 300 300 Å 0.8 ml/g 100 m2/g 0.45 g/ml 400 bar
POLYGOPREP 1000 1000 Å 0.8 ml/g 25 m2/g 0.45 g/ml 300 bar

Adsorbents for column chromatography

Application Adsorbent
Fluorescence indicator adsorption procedure Silica FIA
Separation of lipophilic substances Standard silica
Separation of lipophilic substances Aluminium oxide
Mainly sample preparation Florisil
Separation of lipophilic and hydrophilic substances Polyamide 6
Separation of hydrophilic substances Cellulose

Silica adsorbents for column chromatography


Standard silica 60, pore size ~ 60 Å, pore volume ~ 0.75 mL/g, spec. surface BET ~ 500 m2/g; highly porous, amorphous silicic acid in the form of hard, opalescent particles, prepared by precipitation of water glass with sulfuric acid

Silica FIA for the fluorescence indicator adsorption procedure for the determination of hydrocarbon groups in the testing of liquid fuels in accordance with DIN 51791 and ASTM D 1319-58T

The FIA method determines saturated hydrocarbons, olefins and aromatic hydrocarbons of a sample chromatographically by adsorption and desorption in a column filled with FIA silica, in the presence of a fluorescent dye mixture

Available Pack Size: 1Kg, 5Kg,25Kg

Aluminium oxide


Aluminium oxides produced by dehydration of different aluminium hydroxides, e.g., hydrargillite between 400 and 500 °C

Activity grade I, particle size 50–200 μm, specific surface (BET) ~ 130 m2/g

Available Pack Size: 1Kg, 5Kg,25Kg



Naturally occurring amorphous silicic acids of fossil origin, also known as diatomaceous earth or diatomite; purified for chromatographic applications
Compared to silica, kieselguhr has a small surface of low activity → application in partition chromatography; impregnated with various substances (paraffin, silicone oil, undecane) it can be used for reversed phase chromatography The following grades of kieselguhr are manufactured by Johns-Manville. They are narrowly classified with homogeneous particle size distributions and high purity.

Available Pack Size: 1Kg, 5Kg



Hard granular magnesia silica gel: MgO 15.5 ± 0.5 % ∙ SiO2 84.0 ± 0.5 % ∙ Na2SO4 ≤ 1.0 %; 60/100 mesh

Typical application: sample preparation (SPE); clean-up of pesticide residues, separation of chlorinated pesticides, extraction of steroids, sex hormones, antibiotics, lipids etc.

Available Pack Size: 1Kg, 5Kg



Polyamide 6 = ε-aminopolycaprolactam Separation mechanism mainly based on hydrogen bonds Recommended application: separation of phenolic compounds (e.g., isolation of natural products), carboxylic acids, aromatic nitro compounds

Available Pack Size: 1Kg,



Cellulose MN 100: native fibrous cellulose, standard grade, average degree of polymerization 620–680, fiber length (85 %) 20–100 μm, specific surface acc. to Blaine ~ 6500 cm2/g residue on ignition < 10000 ppm, < 20 ppm Fe, < 5 ppm Cu, < 7 ppm P, dichloromethane extract < 0.20 %

Cellulose MN 2100: native fibrous cellulose, purified grade (washed with different eluents), average degree of polymerization 620–680, fiber length (85 %) 20–75 μm, specific surface acc. to Blaine ~ 5500 cm2/g residue on ignition < 1000 ppm, < 2 ppm Fe, < 1 ppm Cu, < 2 ppm P, dichloromethane extract < 0.15 % grade MN 2100ff is a defatted cellulose MN 2100 with a dichloromethane extract < 0.02 %

Available Pack Size: 1Kg,5Kg,25Kg

Spherical bulk silica packing’s for HPLC

NUCLEODUR® high purity silica

  • NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
  • Totally spherical particle shape
  • Outstanding surface microstructure
  • High pressure stability
  • Low metal content
Available Pack Size: 100gm, 1Kg
Phase Modification % C pH range Particle sizes [µm] USP
C18 HTec Octadecyl, high capacity, high density, endcapped 18 1–11 5,7,10 L1
C18 ec Octadecyl, medium density, endcapped 17.5 1–9 10, 12, 16, 20, 30, 50 L1
SiOH Unmodified - 2–8 10, 12, 16,20, 30, 50 L3

NUCLEOSIL® standard silica

  • NUCLEOSIL® is a family of totally porous spherical silica’s with a very pure and uniform SiO2 structure :
  • Wide acceptance as routine packing’s for very different fields of chromatography
  • One of the first spherical silica’s used in HPLC
  • Developed in the early seventies, now a world-renowned HPLC packing
  • Still found in many analytical and preparative applications
  • An absolutely reliable choice in HPLC
  • The largest variety of modified HPLC silica’s available on the market
Available Pore Sizes: 50 Å, 100 Å, 120 Å, 300 Å, 500 Å, 1000 Å, 4000 Å
Phase Modification
NUCLEOSIL® C18 Medium density octadecyl, endcapped
NUCLEOSIL® C18 AB Crosslinkedoctadecyl, endcapped, high steric selectivity
NUCLEOSIL® C8 ec Medium density octyl, endcapped
NUCLEOSIL® C8 Standard octyl, not endcapped
NUCLEOSIL® C4 Medium density butyl, endcapped
NUCLEOSIL® C2 Dimethyl
NUCLEOSIL® C6H5 ec Medium density phenyl, endcapped
Polar Phases
NUCLEOSIL® C6H5 Standard phenyl, not endcapped
NUCLEOSIL® CN Cyanopropyl (nitrile)
NUCLEOSIL® NO2 Nitrophenyl
NUCLEOSIL® OH Diol (dihydroxypropyl)
NUCLEOSIL® NH2 Aminopropyl
NUCLEOSIL® OH Diol (dihydroxypropyl)
NUCLEOSIL® N(CH3)2 Dimethylamino
NUCLEOSIL® SA Benzenesulfonic acid, strongly acidic cation exchanger (SCX)
NUCLEOSIL® SB Quaternary ammonium, strongly basic anion exchanger (SAX)
NUCLEOSIL® SiOH Unmodified
Available Particle Sizes: 3 µm, 5 µm, 7 µm, & 10 µm